Journal of Leukemia
Open Access

Abstract

2Isolated CNS Blast Crisis of CML in A Patient on Dasatinib Therapy

Rehab Al-blooshi, Dimitrios Vergidis and Jeffrey H Lipton

We report a case of a young male with chronic phase CML who despite achieving an excellent response to dasatinib therapy, developed isolated CNS blast crisis even though this tyrosine kinase inhibitor is the only one reported to cross the blood brain barrier.