Journal of Clinical & Experimental Dermatology Research
Open Access

Abstract

A Little Known but Potentially Life-threatening Association of Bullous Pemphigoid and Acquired Hemophilia: Case Report and Review of the Literature

Christine Nguyen, Justin S. Gordon and Anne Lynn S. Chang

While bullous pemphigoid has been associated with a number of medical conditions and drugs, the link with acquired hemophilia (AH) has not been widely reported. AH is a rare yet life-threatening autoimmune disorder with an estimated mortality rate ranging from 8-22%. A PubMed search revealed fifteen cases of AH reported in patients with bullous pemphigoid (BP). Here we describe an additional case of BP in a 49-year-old female who later developed AH, and review the evidence behind this association.