Anatomy & Physiology: Current Research
Open Access

Abstract

A Study of the Effect of Auditory Stimuli on GLP1, Insulin, Liptin and Body Weight of Crowded Adult Albino Rats

Ahmed A.Abd El-Rhman*, Mohamed Z.Al-Etreby, Ali A.Khalil, Mohamed Fawzy and Abd El-Megeed Mansour

Background: Music therapy is an established health profession in which music is used within a therapeutic relationship to address physical, emotional, cognitive and social needs of individuals. Stress is the reaction of the organism to stimulus which changes psycho-physiological equilibrium with harmful consequences. This disturbance leads to changes in the concentration of large number of different hormones that have a crucial role on homeostasis.

Objectives: The current study was designed to clarify the possible effect of enhancing the quality of environment to alleviate the stressful environmental condition.

Material and Methods: Forty-five adult male albino rats were chosen for this study. They were divided into five groups as follows:

Group 1: Served as normal control rats.

Group 2: Rats exposed to crowding.

Group 3: Rats exposed to crowding and listening to instrumental music.

Group 4: Rats exposed to crowding and listening to soft song.

Group 5: Rats exposed to crowding and listening to rallying song.

After 90 days all rat groups were anesthetized, and blood sample collected for measurement of Glucagon Like Peptide 1(GLP1) level, Insulin level, Leptin level and specimens from pancreas were fixed for histopathological examination for these groups and all pancreas sections were examined using light microscope.

Results: Music has no significant (P<0.05) effect on water and food consumption but it has significant (P<0.01) effect on body weight in music listening groups in comparison with control crowded group. Music listening can significantly (P<0.01) increase level of GLP1 and leptin but significantly (P<0.01) decrease level of insulin in comparison with control uncrowded group.

Conclusion: Music may alleviate the stressful situation and improve quality of life.

Published Date: 2022-11-01; Received Date: 2022-09-20