Reproductive System & Sexual Disorders: Current Research
Open Access

Abstract

ADAM12: The Usual Suspect in Preeclampsia

Hemant Kulkarni

Burgeoning evidence is now pointing towards a potential role of the ADAM12 gene in preeclampsia. A closer scrutiny of this evidence, however, shows that many important questions remain unanswered. As a result, the genetic jigsaw of preeclampsia is a poser far from solved. Continued efforts are required to investigate this gene, especially in the context of its involvement in the transforming growth factor signaling pathway.