Journal of Cell Science & Therapy
Open Access

Abstract

Adipose-Derived Stem Cells, their Secretome, and Wound Healing

Sherry S Collawn and Shyam Patel

Adipose tissue is an abundant source of progenitor cells with multidifferentiation potential and these cells, termed adipose-derived stem cells (ASC), have become an important proposed treatment for use in wound healing. The ability of these cells to increase angiogenesis (vessels arise from other vessels) and vasculogenesis (vessels arise from progenitor cells), produce growth factors and cytokines, produce cell matrix proteins, and increase cell proliferation place them in a unique position to improve wound healing.