Andrology-Open Access
Open Access

Abstract

Age-dependent Expression of Catspers in Human and Mice Sperm

Sriram Seshadri, Kaveri Purandhar and Nivedita Pareek

Catspers are crucial for sperm functioning and its motility. This study brings forth the differential expression of Catsper 1, 2 and 4, irrespective of the species. The expression is studied in ejaculated human and mice testicular sperm with progression of age. Decreased expression of Catsper 1 was found in both the study subjects. In contrast, Catsper 4 expression decreased in human while Catsper 4 did not show any trend in mice. It can be concluded that the Catsper 1 can be used as a marker for aging and male infertility.