Journal of Clinical Chemistry and Laboratory Medicine
Open Access

Abstract

Analysis of Alcohol Consumption on Gastric Cancer in Different Infectious States of Helicobacter pylori in the Wuwei Population, China

Bilembi Mbote Olivier*, Boxi Feng, Yubo Zhou, Mingyu Zhang, Yindi Wang, Zhen Lv, Sansan Li, Yahui Xie, Xingmin Wei, Jianjun Wu and Yuqin Liu

Aim: The study aims to examine the correlation between alcohol consumption and the risk of gastric cancer in the Wuwei population with different levels of H. pylori infection.

Methods: The study included 3123 participants aged 40-70 years who had resided in Wuwei city for at least 5 years. Participants completed questionnaires on personal information, diet, alcohol consumption, family and medical history and H. pylori detection. All participants underwent 13C-Urea Breath Test (13C-UBT) for H. pylori infection and upper gastrointestinal endoscopy and pathology were performed. Testing was conducted before diagnosis to avoid recall bias.

Results: Alcohol increases the risk of gastric cancer, but it decreases the risk in those who are infected. Those aged 50-70 without H. pylori who consume alcohol and smokers who quit with H. pylori infection have a higher risk of gastric cancer.

Conclusion: Alcohol consumption represents a significant risk factor for the development of gastric cancer. This risk is particularly pronounced with advancing age and following the eradication of H. pylori.

Published Date: 2024-08-13; Received Date: 2024-07-12