Medicinal & Aromatic Plants
Open Access

Abstract

Antipruritic Ointment Randia Monantha

Cesar Palacios Ramos, Adan Bulmaro Serrano García, Mirna Lorena Sánchez and Arianna Beatriz Gallegos Pineda

Objective: Obtain Randia Monantha Benth extract, use it as the main component in the formulation of an ointment with antipruritic characteristics. Investigate and analyze its effect through microbiological, activity, validation, and sensory assays.
Methods: Soxhlet process with different solvents was performed to obtain the extract.
Results: Comparing the different solvents (petroleum ether, acetone and ethanol). It was determined that the best solvent for extraction is 20% ethanol. After the different experiments, the ointment made of Randia Monantha Benth presented no contamination through the microbiological assay. Using statistical technique ANOVA along with the activity tests it was proved that the application of the ointment can reduce the pruritic effect.
Conclusion: The use of Randia Monantha Benth extract as part of a formulation was possible, antipruritic effects were successful and the results obtained suggest a favorable potential for future tests and research.