Annals and Essences of Dentistry
Open Access

Abstract

APPLICATION OF STEM CELLS IN ORTHODONTICS : A REVIEW

Srinivasa Rao Kolasani, Sreevalli S

The purpose of this article was to review and update current data of the use of stem cells for dental but specifically orthodontic purpose. Interest regarding stem cell based therapies for the treatment of congenital or acquired craniofacial deformities is rapidly growing. Craniofacial problems such as periodontal disease, cleft lip and palate, ear microtia, craniofacial microsomia, and head and neck cancers are not only common but also some of the most burdensome surgical problems worldwide. Treatments often require a multi-staged multidisciplinary team approach. Current surgical therapies attempt to reduce the morbidity and social/emotional impact, yet outcomes can still be unpredictable and unsatisfactory. The concept of harvesting stem cells followed by expansion, differentiation, seeding onto a scaffold and retransplanting them is likely to become a clinical reality. In this review, the translational applications of stem cell therapy in tissue regeneration for craniofacial defects are summarized.

Published Date: 2016-09-30;