Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
Background: New molecular docking software is a technical approach that is mostly employed in drug discovery and design, as well as for numerous analysis processes. Computerized platforms are used in the process of molecular docking. It is a molecular combination in which one molecule binds to other molecules to form a bonded complex with all-around lowest energy requirements.
Cannabidiol (CBD) has blowup in fame around the world in just a few years. Cannabidol is currently vended and used to give a wide range of therapeutic illnesses and lifestyle diseases after being revealed as an effective selfmedication for Dravet syndrome in progenies. Cannabidol, a non-psychoactive isomer of the more well-known Tetrahydrocannabinol (THC), is becoming increasingly widely accessible in a variability of forms.
Result: Using several molecular docking techniques, the current study seeks to investigate the binding interactions of delta-9 THC with cytochrome p450. CYPs are a family of mono oxygenases that contain heme as a cofactor. The findings of docking tests revealed that these compounds have high binding affinities. The mechanism and interactions are the focus of this research.
Conclusion: It aids computer-based concepts, which provide new ideas to staff in investigating and bringing theories together experimentally, as well as bringing answers to all difficulties, including cost, that arise.
Published Date: 2023-04-27; Received Date: 2023-01-18