Global Journal of Life Sciences and Biological Research
Open Access

Abstract

Biotechnology, Biomarkers & Systems Biology 2019: Evaluation of Magnetic Field Influence on Chinese Hamster Ovary Cells - A. Rekena - Rudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU

A. Rekena1, D. Livkisa2, D. Loca3

The influence of magnetic field on mammalian cells and their biotechnological properties has been widely investigated. Several mammalian cells dominate the industry as measured per number of products in the market. Previously, Chinese hamster ovary (CHO) cells have demonstrated increased cell permeability, gene expression, proliferation and micronuclei formation after magnetic field exposure. On the contrary, it has been reported that the cell survival and growth rate, cell cycle distribution and mutation frequency are not influenced. The purpose of this study is to evaluate magnetic field influence on mammalian cell CHO-S proliferation by application of a static magnetic field generated by permanent magnets.

Published Date: 2021-06-21;