Journal of Clinical & Experimental Dermatology Research
Open Access

Abstract

Can Atopic Dermatitis in Dogs Be Associated with Intestinal Inflammation?

Mahmut OK*

The aim of this study is to investigate the relationship between atopic dermatitis and intestinal inflammation in dogs, highlighting the potential role of mucosal epithelial barrier damage in the development of the disease.

The study reviews the current literature on atopic dermatitis in dogs, focusing on the role of environmental and food allergens, as well as the potential contribution of intestinal inflammation and damage to the development of the disease. Biomarkers such as Intestinal Trafoil Factor 3 (ITFF-3), Intestinal Alkaline Phosphatase (IAP), Immunoglobulin E (IgE), Interleukin-4 (IL-4), and Interleukin-13 (IL-13) are discussed in relation to their potential use in diagnosing and managing atopic dermatitis.

The study highlights the significant correlation between atopic dermatitis and intestinal inflammation in dogs. Elevated levels of ITFF-3 and IAP biomarkers are associated with epithelial damage in the intestine and may indicate the presence of leaky gut syndrome. The study suggests that correcting intestinal microbiota and repairing intestinal damage through treatments such as oral faecal microbiota transplantation may be beneficial in managing atopic dermatitis.

In conclusion, the study emphasizes the importance of considering the role of intestinal inflammation and damage in the development of atopic dermatitis in dogs. The use of biomarkers such as ITFF-3 and IAP can help diagnose and monitor the disease. Additionally, the study suggests that incorporating treatments that correct intestinal microbiota and repair intestinal damage into the standard treatment plan may be beneficial in managing atopic dermatitis. Further comprehensive studies are needed to fully understand the relationship between atopic dermatitis and intestinal inflammation in dogs.

Published Date: 2024-07-05; Received Date: 2024-06-04