Gynecology & Obstetrics
Open Access

Abstract

Cervical Cancer: Prognostic and Evolution after Radiotherapy (Results from a Single Institution)

Sahli N, Khalil J , Elkacemi H , Lachgar A , Razine R ,Kebdani T, Elmajjaoui S ,and Benjaafar N

Introduction: In Morocco, cervical cancer is the second most common cancer,and the third cause of death. Our department recruits more than 500 patients each year and proximally half of the cases are diagnosed at an advanced stage.

Patients and methods: Between January 2011 and December 2011, all patients diagnosed with cervical cancer and treated with concurrent chemoradiotherapy were retrieved. We analyzed overall survival, local control, and defined prognostic factors influencing outcomes in this population.

Results: At 3 years the overall survival rate for the cohort was 89.8% and the overall LC rate was 80.8%. The most important prognostic factors for OS and LC were the pretreatment hemoglobin, total duration of treatment, and the use of brachyteherapy. Of the included patients, 20% experienced late Grade 3 or 4 toxicity.

Conclusion: The results of our study have shown that besides tumor stage, the use of brachytherapy, and lymphnode status, other factors such as pretreatment hemoglobin and treatment duration should be analyzed carefully and should be considered taking into consideration influence of all of the aforementioned factors.