Medical & Surgical Urology
Open Access

Abstract

Clinical, Etiology and Antibiotic Susceptibility Profiles of Community-Acquired Urinary Tract Infection in a Baghdad Hospital

Hussein NS

Objective of the study: To analyze clinical presentation, etiology and antibiotic sensitivity of bacteria causing Community Acquired Urinary Tract Infection (CA-UTI) among our patients to provide data that could guide empiric treatment.

Material and Methods: Outpatients urine cultures and clinical presentations were collected from April 2012 to October 2012. A positive urine culture was defined as growth of a single bacterium with colony count of more than 100,000 CFU/ml and disk diffusion technique according to Clinical and laboratory standards institute (CLSI) was performed to determine antibiotics susceptibility of isolated bacteria species. Clinical symptoms, causative uropathogens and their antibiotic sensitivity were recorded.

Results: Of 299 urine cultures processed, a positive urine culture was detected in 100 subjects. Dysuria and bladder irritability (frequency and urgency) were the most common clinical presentation, but were no specific in predicted CA-UTI. Escherichia coli (39%) and Staphylococcus strains (30%) were the most organisms causing CAUTI s. The isolated organisms showed a substantial sensitivity reduction to most of test antibiotics.

Conclusion: Clinical presentation had a minor in diagnosis of CA-UTI and this study revealed that E.coli and Staphylococcus strains were the most prevalent isolated uropathogens among our population. Susceptibility test showed there was a high sensitivity to nitrofurantoin, amikacin and imipenem with reduction sensitivity to other commonly used antibiotics brings a concern for future studies to guidance empirical treatment.