Journal of Medical Diagnostic Methods
Open Access

Abstract

Clinical Research for the Treatment of Tubal Obstructive Infertility by Fallopian Tube Recanalization Combined with Traditional Chinese Medicine

Xiao-ping Pan, Ya-ping Zhang and Yao-chun Hu

Objective: To observe the clinical curative effect of Fallopian Tube Recanalization combined with Traditional Chinese Medicine and to explore the mechanism of Traditional Chinese Medicine in the treatment of Tubal Obstructive Infertility.

Method: We selected 180 patients with Tubal Obstructive Infertility and randomly divided them into 3 groups, each group contained 60 subjects. The subjects of the first group received treatment of Fallopian Tube Recanalization combined with Traditional Chinese Medicine, the second group received Fallopian Tube Recanalization alone and the third group received Traditional Chinese Medicine alone. Then we observed the success rate of each group according to their Fallopian tube patency rate, pregnancy rate and Fallopian tube re-adhesion formation rate.

Result: (1) The success rate of the first group was 81.7%, while that of the second group was 78.3%, and 56.7% for the third group. There was a significant difference between the first group and the third group, as well as the second group and the third group (P<0.05). (2) One year’s follow-up after treatment showed the pregnancy rate (defined as numbers of pregnancy over numbers of successful recanalization procedures) of the first, second and third group were 65.3%, 53.2% and 64.7% respectively. Although there was no significant difference between these 3 groups, the pregnancy rate of the two groups which applied Traditional Chinese Medicine was higher than the group which applied recanalization procedure alone. (3) One year after treatment, there were 5 Fallopian tube re-adhesion cases in the first group, 12 cases in the second group and 5 cases in the third group, the re-adhesion rate was 10.2%, 25.5% and 14.7% respectively. There was a significant difference between the first group and the second group (P<0.05).

Conclusion: Interventional Fallopian Tube Recanalization can increase the rate of patency of occluded Fallopian tube, while Traditional Chinese Medicine can decrease post-operational tubal re-adhesion formation rate and facilitate pregnancy. The two treatments can be combined to treat Tubal Obstructive Infertility.