Hair Therapy & Transplantation
Open Access

Abstract

Current Approach for Keratin-Mediated Hair Growth

Yu-Shik Hwang*

Keratin, an essential structural protein in epithelial cells, plays an important and complex role in hair growth and regeneration. In addition to its recognized structural features, keratin plays a role in several biological processes important for hair follicle development, Dermal Papilla (DP) cells, by releasing paracrine factors, direct the migration and differentiation of stem cells into matrix cells, which ultimately commence follicle formation. Keratin synthesis in the hair cortex is essential for the mechanical strength and structural integrity of the hair shaft. Recent research has revealed that keratin-based biomaterials, specifically keratin derived from human hair, can promote therapeutic approaches, including keratin injectable, keratin-based microneedle patches and keratin microspheres, have demonstrated encouraging results in promoting hair growth and wound healing. This review provides information of current approaches of keratin-based treatments to improve hair growth.

Published Date: 2024-12-12; Received Date: 2024-11-12