Orthopedic & Muscular System: Current Research
Open Access

Abstract

Current Progress in Enthesis Repair: Strategies for Interfacial Tissue Engineering

Jennifer Z. Paxton, Keith Baar and Liam M.Grover

Complex interfaces have evolved at the junction between tissues of the musculoskeletal system to overcome
the problems of impedance mismatch. In this review, we have revisited the anatomy, development, injury and repair
of the interface between bone and tendon/ligament, also known as the osteotendinous/osteoligamentous junction
or enthesis. Specifically, the existing options for repair have also been discussed along with the current progress of
interfacial tissue engineers aiming to manufacture multiphase tissue constructs for repair of these complex interfaces
in vitro.