Journal of Clinical & Experimental Dermatology Research
Open Access

Abstract

Diagnostic Accuracy of Dermoscopy in some Hypopigmented Lesions on Patients Referred to the Farshchian (Sina) Hospital

Nayereh Gholizadehfard*, Mohammadreza Sobhan, Ghodratollah Roshanaei, Pedram Alirezaei and Seyede Parmis Maroufi

Objective: This study aimed to evaluate the diagnostic accuracy of dermoscopy in patients with some hypopigmented lesions.

Material and methods: 150 patients with hypopigmented skin lesions were included in the study, of which 22 were excluded due to previous treatments. Finally, 128 patients with hypopigmented skin lesions and a possible diagnosis of cutaneous discoid lupus erythematosus, morphea, extragenital lichen sclerosis, and idiopathic guttate hypomelanosis were biopsied after dermoscopic examination to confirm the diagnosis.

Results: The patients evaluated were as follows: Discoid lupus erythematosus (19 cases), morphea (25 cases), extragenital lichen sclerosis (4 cases), and idiopathic guttate hypomelanosis (13 cases) and 67 other diagnoses as control groups were considered separately to compare dermoscopic parameters in each group. The most common dermoscopic findings in discoid lupus erythematosus were telangiectatic vessels in 68.4% of patients. The sensitivity and specificity of dermoscopy in diagnosing were 94.7% and 35.5%, respectively. The most common findings in morphea were white fibrotic beams in 56% of patients. The sensitivity and specificity of dermoscopy in diagnosing morphea, considering only one variable, were 100% and 33%, respectively. The most common finding in extragenital lichen sclerosis was bright white-yellowish plaque in 100% of cases. The most common finding of idiopathic guttate hypomelanosis was nebuloid pattern in 69.2% of patients. The sensitivity and specificity of dermoscopy in diagnosing idiopathic guttate hypomelanosis were 100% and 38.7%, respectively.

Conclusion: The results of this study show that dermoscopy has high sensitivity and low specificity in patients with hypopigmented lesions.

Published Date: 2024-05-03; Received Date: 2024-04-01