Journal of Clinical & Experimental Dermatology Research
Open Access

Abstract

Epidermolysis Bullosa Acquisita: A Case Report

Lafuente Cevallos Lizeth Verónica*, Ureña López Valeria Alexandra, Lascano Gallegos Nathalie and Palacios Alvarez Santiago Alberto

Epidermolysis Bullosa Acquisita (EBA) is a chronic autoimmune subepidermal blistering disease developed after damage to type VII collagen by autoantibodies. Type VII collagen is the major component of anchoring fibrils in the sub-lamina densa hemidesmosomes of the skin and squamous mucosas. The worldwide incidence is estimated between 0.2-0.5/million inhabitants per year. Two major clinical variants have been described: the mechanobullous, and the inflammatory EBA.

Published Date: 2020-12-25; Received Date: 2020-12-04