Annals and Essences of Dentistry
Open Access

Abstract

EVALUATION OF CLINICAL EFFICACY OF FLUCONAZOLE MOUTH RINSE FOR TREATMENT OF ORAL CANDIDIASIS

Ramesh DNSV, Jitender Reddy K

Oral Candidiasis is associated with multiple local and systemic factors. Morbidity and death in high risk patients may be prevented by recognition and adequate management.Flluconazole in a systemic antifungal medication that demonstrate clinical advantage in rinsing before swallowing. The purpose of present study was to evaluate the clinical efficacy of fluconazole aqueous mouth rinses to treat oral candidiasis.AIM: To evaluate the clinical efficacy of fluconazole mouth rinse for treatment of oral candiadiasis. Objectives: 1) To verify the mycological cure achieved by the drug supported clinical and candida culture.2) To determine the side effects associated with drug. Material and Methods - This study group consists of 30 patients who were clinically diagnosed as oral candidiasis and the subjects used 5 ml fluconazole ( 2mg/ml ) mouth rinse 3 times per day rinsing a minimum of 2 minutes and spitting it. The clinical out come and possible adverse effect were assessed after two weeks of treatment.Results: Follow –up done for the 30 patients. Complete systematic and clinical relief was noted in 86.66% and mycological cure in 73.3% of the patients. No side effects were reported. Conclusion: The use of fluconazole mouth rinses appears to be well tolerated and it is helpful in the treatment of oral Candidiasis effectively.

Published Date: 2010-12-31;