Annals and Essences of Dentistry
Open Access

Abstract

Evaluation of Photodynamic Therapy in Comparison with Conventional Treatment for the Treatment of Periodontal Disease: A Clinical Trial

Iram Rafique Pawane* and Jaiganesh Ramamurthy

Aims: The aim of this study was to compare the clinical results of conventional non-surgical periodontal therapy with or without adjunct PDT in patients of chronic periodontitis.

Materials and methods: 20 patients with chronic untreated periodontitis, (8 female, 12 male, mean aged: 36.35 years, all non-smokers, systemic diseases, including anti-inflammatory, blood stimulants, or systemic antibiotics, within the last 6 months were exempted from the criteria, previously untreated chronic periodontitis; in any quadrant at least 1 premolar and 1 molar with at least 4 teeth each; in each quadrant at least 1 tooth with an attachment loss of >3 mm were included in the study. The periodontal status of each subject was evaluated at baseline and 6 weeks following periodontal therapy. PDs, Clinical Attachment Level (CAL) were assessed.

All patients received non-surgical periodontal treatment comprising a thorough scaling and root planing of all periodontally involved teeth using a split-mouth design, two quadrants were additionally treated with PDT, with a designated photosensitizer dye (methylene blue) and a diode laser (biolase 940 nm). Laser application at six locations per tooth was carried out circumferentially. The subjects were given thorough oral hygiene maintenance instructions and recalled after two weeks for a second round of PDT at the same sites. A total of two exposures for the photodynamic therapy group with a two week interval were done Probing depths and attachment levels were assessed after 6 weeks. Statistical analysis was done to compare intergroup using the paired t-test. Differences were considered as statistically significant at p<0.05.

Results: Baseline mean values for PD and CAL were significantly different in the test and control group. Values for CAL and PD decreased significantly 6 weeks after treatment in the control group, with a higher impact on the sites treated with adjunctive PDT

Conclusion: In patients with untreated chronic periodontitis, clinical outcomes of conventional non-surgical periodontal therapy can be improved by multiple PDT.

Published Date: 2021-12-22; Received Date: 2021-12-01