Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Burn injuries pose a significant public health challenge, particularly in conflict-affected regions, leading to debilitating functional and cosmetic impairments. Current treatment options include debridement, skin grafts, and silicone therapy, but they have limitations in addressing the complex nature of burn wounds. Stem cell therapy, especially using Mesenchymal Stem Cells (MSCs), offers a potential avenue for enhancing natural skin regeneration processes. MSC-based therapy has demonstrated efficacy in promoting wound healing by modulating inflammation, promoting angiogenesis, and facilitating tissue regeneration. Various stem cell sources, such as Adipose-Derived Stem Cells (ADSCs), Bone Marrow-Derived MSCs (BM-MSCs), and umbilical cord blood MSCs, have been explored for their therapeutic potential in burn wound management. Despite the potential outcomes, challenges such as protocol standardization, long-term follow-up, and patient selection optimization persist. Nonetheless, stem cell therapy holds significant potential for revolutionizing burn injury treatment and improving patient outcomes. Further research is needed to elucidate the underlying mechanisms and optimize treatment strategies for effective translation into clinical practice.
Published Date: 2024-05-03; Received Date: 2024-04-01