Journal of Cancer Research and Immuno-Oncology
Open Access

Abstract

Human Mesenchymal Stem Cell Transfusion for End Stage Liver Disease: A Case Series and Literature Review

Wen-Bo Meng, Bing Bai, Ying Li, Jian-jun Zhang, Yong-long Guo, Wen-Ce Zhou, Yan Li and Xun Li

Decompensated liver cirrhosis is a severe, life-threatening situation in end-stage liver disease. Liver transplantation is the only effective therapy regarding on this. Unfortunately the shortage of liver donors, vast of patients died during enrolled in the waiting list. There are increasing reports of using stem cell to treat advanced liver disease nowadays worldwide, and if it could be alternative therapy in persons with end-stage liver disease is not so clear. Herein we describe a case series outcome of Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs) transfusions for decompensated liver cirrhosis and also reviewed the literature on stem cell therapy.