Journal of Drug Metabolism & Toxicology
Open Access

Abstract

Hydrophilic interaction liquid chromatography (HILIC)

S Harshitha, R surya santhosh, SK. Baba Hussain, K S Natraj, A Srinivasa rao

Hydrophilic interaction liquid chromatography (HILIC) is a variant of normal  phase liquid chromatography  provides  that partly overlaps with other chromatographic applications such as ion chromatography and  reverse phase liquid chromatography a way to separate small polar compounds on polar stationary phases effectively. The purpose of this work was to review the characterization of HILIC stationary phases and their applications and its column chemistry and also method development as HILIC increases the scope of possible applications of liquid chromatography.

Published Date: 2020-09-25; Received Date: 2020-07-29