Journal of Leukemia
Open Access

Abstract

IgA Plasma Cell Leukemia: A Rare Case

Ed-Dyb S*, Aznag MA, Rouhi S, Ed-Dyb S, Aznag MA, Rouhi S, Yahyaoui H, Raissi A, Ait Ameur A, Ait Ameur A, Chakour M, Chakour M, Boukhira A, Boukhira A*, Chellak S* and Chellak S

Plasma cell leukemia (PCL) is a rare entity. It is classified as either primary PCL occurring at diagnosis or as secondary PCL in patients with multiple myeloma (MM). The PCL is a rare disorder representing 1-2% of the diagnosed cases of MM. The median age is above 50 years. The electrophoresis shows a monoclonal protein in patients with PCL that is usually IgG (50%), IgA (15%), or in rare cases IgD or IgE (6%). Due to the rarity of this condition, only a few cases have been reported in the literature. It is characterized by its aggressiveness and poor prognosis. Through this case diagnosed in our laboratory we will describe the biologic particularities and prognosis of IgA primary PCL.

Published Date: 2021-03-26;