Mycobacterial Diseases
Open Access

Abstract

Impact of Alcohol Consumption on Tuberculosis Mortality in Young Mice

Nese Chiera*

Tuberculosis (TB) remains one of the leading infectious diseases worldwide, particularly affecting individuals with weakened immune systems. While human studies have established a link between alcohol abuse and increased susceptibility to TB, research on the effects of alcohol in experimental animal models, such as mice, provides deeper insight into how alcohol impacts TB progression and mortality. This content focuses on recent research exploring the relationship between alcohol consumption and tuberculosis deaths in young mice, shedding light on the underlying mechanisms and potential implications for human health. Alcohol is a well-known immunosuppressant that weakens the body's ability to fight infections. In people who abuse alcohol, the immune system’s defenses are compromised, making them more vulnerable to infections like TB. Chronic alcohol consumption has been linked to impaired lung function, poor immune response, and an increased risk of respiratory infections. In the context of tuberculosis, these immune deficiencies can lead to faster disease progression and higher mortality rates. Young mice serve as an important animal model in TB research because their immune systems are still developing, similar to human infants and children. Researchers use these models to study how alcohol consumption affects TB infection, immune response, and survival rates in young subjects.

Published Date: 2024-10-03; Received Date: 2024-09-04