Journal of Clinical and Cellular Immunology
Open Access

Abstract

Impact of Eosinophilic Inflammation in Chronic Rhinosinusitis

Mark Jansen

Chronic Rhino Sinusitis (CRS) is a persistent inflammatory
condition that affects the mucous membranes of the nasal cavity
and paranasal sinuses. It is diagnosed based on symptoms lasting
at least 12 weeks, such as nasal congestion, facial pain, olfactory
disturbances and nasal secretions. CRS can present in two
distinct forms: with polyps and without polyps. The key
difference between these two forms lies in their symptoms and
inflammatory characteristics. CRS with polyps often involves
hyposmia and eosinophilic inflammation, while CRS without
polyps is frequently associated with facial pressure, a neutrophilic
inflammatory response and tissue fibrosis.

Published Date: 2024-11-21; Received Date: 2024-10-21