Journal of Cell Science & Therapy
Open Access

Abstract

Impaired Cardiac Function in Cardiac-Specific SIRT1-Deficient Mice

Feng Cao

Cardiac specific SIRT1 knockout mice were generated through the Cre/loxP system. Briefly, loxP-SIRT1 mice and Myh6-Cre mice were crossed to get SIRT1+/- mice.