Journal of Nutrition & Food Sciences
Open Access

Abstract

Influence of Dietary Amino Acid Profile on Serum Lipids in Hypercholesterolemic Chinese Adults

Li Li Ma, Gui Yuan Ji and Zhuo Qin Jiang

To investigate the significance of Lys:Arg and Met:Gly ratio on serum lipids concentrations and adiponectin in hypercholesterolemic adults, 24 g of soy isolate protein supplement (SIP) or milk protein supplement (CON) were randomly given to 90 subjects (n=45/group) daily for 8 weeks. The correlation between dietary proteins, Lys :Arg and Met:Gly ratio and the percentage changes in lipids and adiponectin in 90 subjects were examined. The percentage changes in total and LDL cholesterol concentrations were significantly positively correlated with the ratio of dietary vegetable protein/animal protein (VP/AP) (rs=-0.595, P<0.001 and rs=-0.606, P<0.001 respectively). The changes of total and LDL cholesterol concentrations were significantly correlated with dietary Lys:Arg ratio (rs=0.574, P<0.001 and rs=0.582, P<0.001 respectively). The change in adiponectin was negatively correlated with dietary Lys:Arg and Met:Gly ratio (rs=-0.668, P<0.001 and rs=-0.309, P=0.003 respectively) and was positively correlated with the ratio of VP/AP (rs=0.566, P<0.001). Vegetable protein diet with low Lys :Arg ratio may have a favorable effect on serum total cholesterol, LDL cholesterol and adiponectin.