ISSN: 2564-8942
Ashraf Abdullah Saad*
Hematologic malignancies, commonly referred to as liquid tumors, encompass a diverse group of cancers such as leukemias, lymphomas, and myelomas. Defined by unique genetic, molecular, and clinical characteristics, these diseases present significant challenges in diagnosis, treatment, and prognosis. Despite advances in therapeutic strategies-including immunotherapy, targeted therapies, and hematopoietic stem cell transplantation-patients with high-risk or relapsed disease often face poor outcomes. Notably, Multiple Myeloma (MM) remains an incurable plasma cell malignancy despite recent innovations, underscoring the need for more effective and durable treatment strategies. This article offers a comprehensive review of the classification, pathophysiology, and molecular features of liquid tumors, with a particular focus on emerging therapeutic approaches and unmet clinical needs. By addressing current challenges and future opportunities, this work seeks to contribute to the advancement of care for patients with these complex malignancies.
Published Date: 2024-11-05; Received Date: 2024-09-26