Angiology: Open Access
Open Access
ISSN: 2329-9495
+44 1478 350008
ISSN: 2329-9495
+44 1478 350008
Wang Qi*, Liu Haiping, Pan Youlong and Hu Jinping
Objective: To evaluate the diagnostic value of cardiac color ultrasound combined with carotid ultrasound for coronary heart disease.
Methods and methods: Computerized search of China Knowledge Network (CKN), Wanfang Medical Network (WMN), Wipo database, Chinese Biomedical Database (CBM), Embase, Pubmed, to retrieve the diagnostic value of cardiac color ultrasound combined with carotid ultrasound on coronary heart disease, the search time is up to August 2023, in accordance with the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) standard for quality evaluation of the included literature, 2 reviewers in accordance with the inclusion and exclusion criteria independently screened the literature, extracted the information and evaluation. After the quality of the included studies was evaluated, meta-analysis was performed using StataSE 15 (64-bit) to summarize the sensitivity and specificity, perform sensitivity analysis and heterogeneity test, and plot the subjects' operating characteristics by Receiver Operating Characteristic curve (ROC).
Results: Eleven papers, including 1432 patients, were finally included. Coronary angiography was used as the standard. Meta-analysis using a random-effects model showed a combined sensitivity of 0.95 [95% CI (0.93, 0.96)], specificity of 0.88 [95% CI (0.70, 0.96)], positive likelihood ratio of 16.8 [95% CI (5.7, 49.1)], and negative likelihood ratio of 0.05 [95% CI (0.03, 0.07)], and the area under the Summary Receiver Operating Characteristics (SROC) curve AUC=0.96.
Conclusion: Cardiac ultrasound combined with carotid ultrasound has good sensitivity and specificity for the diagnosis of coronary artery disease, but in actual clinical practice, it is still necessary to refer to other relevant laboratory tests and specific clinical manifestations for diagnosis.
Published Date: 2024-06-14; Received Date: 2024-05-14