Journal of Cell Science & Therapy
Open Access

Abstract

Metabolic Syndrome

Mukund R Mogarekar, Mohit V Rojekar and Swati D Sawant

The metabolic syndrome (MetS) is a constellation of interrelated risk factors of metabolic origin - metabolic risk factors - that appear to directly promote the development of atherosclerotic cardiovascular disease (CVDs). It consists of atherogenic dyslipidemia (elevated triglycerides and apolipoprotein B-containing lipoproteins and decreased high-density lipoproteins [HDL]), elevations of blood pressure (BP) and glucose, and prothrombotic and proinflammatory states. The review focuses on epidemiology, pathophysiology of the MetS. Metabolic syndrome is discussed with respect to developmental (childhood and infancy) aspects, genomics and mechanisms of carcinogenesis.