Journal of Clinical and Experimental Ophthalmology

Journal of Clinical and Experimental Ophthalmology
Open Access

ISSN: 2155-9570

Abstract

Ocular Manifestations of HIV Infection

Malciolu-Nica Maria-Alexandra*

Human Immunodeficiency Virus (HIV) is a retrovirus which by the gradual decrease in CD4+ T lymphocytes causes Acquired Immune Deficiency Syndrome (AIDS). Ocular diseases are common in both asymptomatic HIV positive patients and those with profound immunosuppression with AIDS. Since HAART has been introduced it remarkably reduced AIDS related mortality, but insufficient or improper management can affect the rehabilitation process. The disease runs a severe course, involving multiple organs. Up to 70% of patients infected with HIV will develop some form of ocular involvement, from mild lesions including blepharitis, dry eye and keratitis, to severe ones such as necrotising retinitis with loss of vision or malignancies such as squamous cell carcinoma, Kaposi's sarcoma and lymphoma. Also a lot of these lesions can be the presenting manifestation of the disease.

Published Date: 2025-04-07; Received Date: 2023-11-01

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