Journal of Depression and Anxiety
Open Access

Abstract

Off label Administration of Buprenorphine in the Treatment of Major Depression

Jamshid Ahmadi

Background: Buprenorphine administration is accompanied with speedy-acting antidepressant effects.

Objective: To describe the antidepressant potentials of buprenorphine.

Discussion: Buprenorphine has rapid-acting and continuous antidepressant properties. Buprenorphine intake is associated with enhanced psychoactivity and demotion in depression. Regulation of mood and emotion are seen following buprenorphine administration. Most of the time buprenorphine is well tolerated.

Conclusion: Buprenorphine use can be safe and has fast-acting and continuous antidepressant effects.