Journal of Clinical & Experimental Dermatology Research
Open Access

Abstract

Persistency of Bullous Pemphigoid Lesions on a Burn Scar: A Clinically Proven Locoregional Immune Dysregulation

Lo Schiavo A, Romano F, Alfano R and Ruocco E

A case of a 75 year old woman with drug-induced bullous pemphigoid is reported. Lesions also involved the site of a burn scar. Systemic steroid therapy proved to be effective on all lesions except for the ones located on the burn scar. In this patient the scarred area acted as a ‘vulnerable’ site, not only facilitating the localization of bullae on the scar (Koebner phenomenon), but also rendering these lesions resistant to the steroid treatment that proved to be effective elsewhere. The persistency of bullae precisely and solely on the burn scar features another facet of the immunocompromised district.