Family Medicine & Medical Science Research
Open Access

Abstract

Propolis against Urolithiasis

Timucin Atayoglu A, Guner Atayoglu A, Oguzhan Gunduz, Ismail Evren, Sibel Silici and Noor Buchholz

Urolithiasis is a common presentation in Family Medicine. People who suffer from this problem very often seek natural treatments. Many natural remedies have been used to treat urolithiasis problems throughout history. Propolis is one of the bee products and a potential preventive and therapeutic agent for different health conditions. The aim of this review is to discuss the possibility that propolis may assist the prevention and treatment of urolithiasis as well. Several compounds have been identified in propolis and we reviewed the scientific literature on them to evaluate the potential effect of propolis against urolithiasis. The active components of propolis that have been identified so far mainly include polyphenols and flavonoids. There is a relatively great amount of scientific data on these components showing their anti-inflammatory, XOD-inhibitory, renoprotective, diuretic, anti-microbial, anti-oxidant and immunemodulator activities. The synergistic effect of active compounds of propolis may be promising for urinary stone disease as further studies are encouraged on their bioavailability, stability in different preparations, along with safe and effective doses for prevention or treatment of urolithiasis on animals and human.