Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

+44 1478 350008

Abstract

Pseudoxanthoma Elasticum: Case Report

Ayman Elgendy, Eslam Alshawadfy, Eman Ali, Magdy Afify, Morad Abouelela, Karem Khalil and Ahmed M Elsaidi

Pseudoxanthoma elasticum (PXE) is a hereditary disorder that mainly involves the skin, eyes, and cardiovascular system. We reported a case of pseudoxanthoma elasticum with involvement of neck, axillae, abdomen and thighs, together with angioid streaking of fundi. Skin biopsy specimen was taken and was stained with hematoxylin and eosin (H and E) that revealed fragmentation of the elastic fibers. These features were suggestive of histopathological diagnosis of PXE. We have reviewed other published reports to obtain a better understanding of the genetics, histopathology, vascular and ophthalmological manifestations of pseudoxanthoma elasticum.

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