Journal of Cancer Research and Immuno-Oncology
Open Access

Abstract

Regulation of Focal Adhesions by PI(4,5)P2 and PI(3,4,5)P3 in Cancer Cell Migration

Dhurgham Al-Fahad

Title: Regulation of Focal Adhesions by PI(4,5)P2  and PI(3,4,5)P3 in Cancer Cell Migration

Name: Dhurgham Al-Fahad

Al-Ayen university, schoole of medical and health technology, Iraq

Abstract
Phosphoinositides and their downstream signalling molecules are involved in adhesion, proliferation and invasion. In this study, MDA-MB-231 breast cancer has been used to investigate the possible role of PI(4,5)P2 and PI(3,4,5)P3 in the regulation of FA turnover.

Firstly, PI(4,5)P2 and PI(3,4,5)P3 have been visualised by PLC

Published Date: 2020-09-18;