Current Synthetic and Systems Biology
Open Access

Abstract

Roles of PARP-1 and PALB2 in controlling deoxyribonucleic acid resection and strand invasion during DSB repair

Jean Masson

Endogenous DNA twofold strand breaks (DSBs) are incredibly
perilous for a cell. Whenever left unrepaired, DSBs can drive
cells to genomic precariousness and tumor improvement. Our
research facility centers around the unpredictable organization of
homologous recombination (HR) catalysts liable for fixing DSBs.

Published Date: 2021-02-26; Received Date: 2021-02-20