Journal of Clinical Toxicology
Open Access

Abstract

Successful Outcome Following a Loading Dose of N-Acetylcysteine to Treat Hepatotoxicity after Repeated Therapeutic Doses of Paracetamol

Abdullah Altamimi, Sami Alshammary, Nidal Malhi, Saleh Almanea and Savithiri Ratnapalan

We describe a case of liver failure in a child with repeated therapeutic doeses of paracetamol after being given multiple doses to manage pyrexia during a viral illness. The child was treated successfully with only a single loading dose of N-acetylcysteine. This case highlights the importance of parental advice and physician vigilance in preventing hepatotoxicity paracetamol overdose during viral illnesses.