Journal of Proteomics & Bioinformatics
Open Access

Abstract

Synthesis, Characterization and Biological Applications of Transition Metal Complexes of [no] Donor Schiff Bases

Khurram Shoaib, Wajid Rehman, Bakhtiar Mohammad and Saqib Ali

Ten novel transition metal complexes of N,O donor ligands have been synthesized by the reaction of ligands with metal acetates in 2:1 molar ratio. These reactions were carried out under reflux in methanol for 3-6 hours. The ligands and their transition metal complexes were characterized on the basis of physical properties, elemental analysis, Infrared spectroscopy, Magnetic susceptibility, Ultraviolet and Atomic absorption spectroscopy and 1H-13C NMR spectroscopy. The FT- IR spectra of the complexes indicated that ligands behaved in bidentate manner coordinating via the nitrogen and oxygen. 1H-NMR and 13C-NMR data of the ligands in pure and complex form confirmed the formation of the complexes. Other analytical techniques demonstrated that transition metal complexes of Cu, Ni, Co and Zn are four coordinated and those of Mn are six coordinated. Furthermore, antibacterial activities have been discussed.