Journal of Clinical and Cellular Immunology
Open Access

Abstract

The Expression of PDCD1 and CD274 in T cells and Macrophages Correlated Positively with COVID-19 Severity

Qianqian Gao*, Shang Liu, Renpeng Ding, Huanyi Chen, Xuan Dong, Jiarui Xie, Yijian Li, Lei Chen, Huan Liu and Feng Mu

The immune responses underlying the infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain unclear. To help understand the pathology of coronavirus disease 2019 (COVID-19) pandemics, public data were analyzed and the expression of PDCD1 (encoding PD-1) and CD274 (encoding PD-L1) in T cells and macrophages were identified to correlate positively with COVID-19 severity.

Published Date: 2020-10-05; Received Date: 2020-09-14