Journal of Physical Chemistry & Biophysics
Open Access

Abstract

The Study of Novel Sulfilimines as Potential Insects Modulators

 Sha Zhou and Zhengming Li

This paper describes the novel sulfiliminyl structures as potential control of the Ca2+ influx within the Ryanodine Receptor of insect body. Referring to commercial Flubendiamide structural composition, N-cyano, N-trifluroacetyl and N-acylamino sulfiliminyl moieties were firstly introduced into dicarboxamides scaffolds. The chiral sulfilimines especially exhibited significant insecticidal activities. The investigation of chirality impact on bioactivity was also systemically studied.