Gynecology & Obstetrics
Open Access

Abstract

The Use of Risk of Malignancy Index for Adnexal Masses

Ismail Kestane, Taylan Senol, Ilker Kahramanoglu and Dilek Kestane

Objective: To evaluate the effectiveness of the Risk of Malignancy Index (RMI) to identify cases with high potential of ovarian malignancy

Methods: A total of 106 patients with adnexal masses were included in this prospective, observational study. The ultrasound findings, menopausal status and serum CA125 level were documented.

Ultrasound characteristics, documented preoperatively, and assessed with RMI scoring to detect the relationship between benign and malign groups. The statistical analysis was done using statistical software (NCSS 2008). The sensitivity, specificity, positive and negative predictive value of serum CA125, ultrasound findings and menopausal status were calculated separately and combined into RMI.

Results: The best cut-off value for the RMI was 189 with a sensitivity of 84.8%, a specificity of 81.6%, a PPV of 78% and a NPV of 87.5%.

Conclusion: The present study demonstrated that RMI was a reliable method detecting pelvic masses with high risk of malignancy. Herewith, RMI leads selecting patients who need to be referred to gynecologic oncologists.