ISSN: 2161-0932
S.V. Ramesar, P. Gathiram, J. Moodley and I Mackraj
Pre-eclampsia is a complex disease that affects both mother and their developing fetus. Due to the multifactorial nature of the disease and its undeciphered etiology, we explore the possibility of improving intrinsic vasodilatory mechanisms as a method of treatment. Reduced utero-placental blood flow seems to be central in the manifestation of this disease leading to the secretions of various factors that maintain and/or worsen the condition. We and various other researchers have showed that improved placental perfusion shows promise in alleviating many symptoms of the disease. This serves as an excellent option at reducing both perinatal and maternal morbidity and mortality irrespective of the predisposing factors for the disease.