Journal of Clinical Trials
Open Access

Abstract

Unraveling the Diagnostic Challenge: Primary Sjögren Syndrome Presenting with Recurrent Fevers and Hypotension

Nidha Shapoo*

Sjogren syndrome is a chronic autoimmune disease with multisystem involvement. The typical sicca symptoms of dry eyes and dry mouth are not always present, and patients may present with a wide range of extra glandular symptoms. In this report, we describe a 31-year-old female who presented with recurrent episodes of fever, malaise, difficulty in swallowing, tachycardia, and hypotension. Her presentation as sepsis led to an extensive investigation of the infectious process, which was negative. The autoimmune workup established the diagnosis of primary Sjogren syndrome. The patient was started on oral corticosteroids and discharged in a stable condition. This atypical presentation of Sjogren syndrome with recurrent fevers and hypotension has not been described before. The case highlights the challenge in diagnosing Sjogren syndrome due to its atypical presentation and multisystem involvement.

Published Date: 2025-02-14; Received Date: 2025-01-14