Journal of Clinical & Experimental Dermatology Research
Open Access

Abstract

Use of Photodynamic Therapy for a Rare Inflammatory Skin Disease: Extragenital Lichen Sclerosus

Luigi Coronella, Lorenzo Scaramuzzino, Nello Tommasino and Giuseppe Lauletta*

Extragenital Lichen Sclerosus (LS) poses diagnostic and therapeutic challenges due to its rarity and varied presentations. This report presents a case of LS affecting the face, resistant to conventional therapies, successfully treated with topical 5-Aminolevulinic Acid (ALA)-Photodynamic Therapy (PDT). A literature review highlights the difficulty in diagnosing extragenital LS and discusses various treatment options, including corticosteroids, calcineurin inhibitors, surgery, and emerging therapies such as ALA-PDT and Janus Kinase inhibitors (JAKi). ALA-PDT emerges as a promising alternative for refractory cases, offering efficacy and safety, while JAKi presents a novel option for longterm management.

Published Date: 2024-05-03; Received Date: 2024-04-01