Journal of Drug Metabolism & Toxicology

Journal of Drug Metabolism & Toxicology
Open Access

ISSN: 2157-7609

+44-77-2385-9429

Volume 3, Issue 4 (2012)

Editorial

Pages: 1 - 5

Autophagy in Toxicology: Defense against Xenobiotics

Wen-Xing Ding

DOI: 10.4172/2157-7609.1000e108

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Research Article

Pages: 1 - 10

Absorption, Distribution and Excretion Pattern of Oral and Transdermal Donepezil Hydrochloride after Single and Repeated Administration to the Rat

Susan R. Meier-Davis, Marie-Eve Rodrigue, Masahiro Yamaji, Yoshiko Katori-Stowell, Jianye Wen, Fatima M. Arjmand, Jutaro Shudo and Tetsuto Nagata

DOI: 10.4172/2157-7609.1000123

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Research Article

Pages: 1 - 10

Effects of Subacute and Subchronic Treatment of Synthetic Plant Growth Regulators on Liver Damage Serum Biomarkers Tissue Antioxidant Defense Systems and Lipid Peroxidation in Rats

Necati Ozok and Ismail Celik

DOI: 10.4172/2157-7609.1000124

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Review Article

Pages: 1 - 5

Methotrexate Side Effects: Review Article

Emna Gaies, Nadia Jebabli, Sameh Trabelsi, Issam Salouage, Rim Charfi, Mohamed Lakhal and Anis Klouz

DOI: 10.4172/2157-7609.1000125

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Research Article

Pages: 1 - 6

Comparative in-vitro Intrinsic Clearance of Imipramine in Multiple Species Liver Microsomes: Human, Rat, Mouse and Dog

Jitendra Kumar Singh, Anant Solanki and Vikas S. Shirsath

DOI: 10.4172/2157-7609.1000126

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Research Article

Pages: 0 - 0

Microsomal Lipid Peroxidation, Antioxidant Enzyme Activities in Brain of Male Rats during Long-Term Exposure to Isoniazid

Ajiboye John Adebayo, Oyagbemi Ademola Adetokunbo, Akintunde Jacob Kehinde, Akinyinka Ebunoluwa Olamide and Arojojoye oluwatosin

DOI: 10.4172/2157-7609.1000127

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Research Article

Pages: 1 - 8

A Fourteen-Day Observation and Pharmacokinetic Evaluation after a Massive Intravenous Infusion of Hemoglobin-Vesicles (Artificial Oxygen Carriers) in Cynomolgus Monkeys

Kazuaki Taguchi, Hiroshi Watanabe, Hiromi Sakai, Hirohisa Horinouchi, Koichi Kobayashi, Toru Maruyama and Masaki Otagiri

DOI: 10.4172/2157-7609.1000128

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Research Article

Pages: 1 - 11

Comparison of Metabolism of Donepezil in Rat, Mini-Pig and Human, Following Oral and Transdermal Administration, and in an In Vitro Model of Human Epidermis

S. R. Meier-Davis, R. Murgasova, C. Toole, F. M. Arjmand, L. Diehl, B. Cayme, J. Wen, J. Shudo and T. Nagata

DOI: 10.4172/2157-7609.1000129

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