Journal of Proteomics & Bioinformatics
Open Access
ISSN: 0974-276X
ISSN: 0974-276X
A. Appa Rao
India
Case Report
A Python Based Hydrophilicity Plot to Assess the Exposed and Buried Regions of a Protein
Author(s): P. Pandarinath, A. Appa Rao and G. Lavanya DeviP. Pandarinath, A. Appa Rao and G. Lavanya Devi
Predicting the antigenic regions of a protein is of prime importance in assessing the states of a polypeptide chain as exposed or buried regions. This can be achieved by calculating and plotting the hydrophilicity of a protein using values of Hoop-Woods scale. Hence, in this paper, we report a hydrophilicity plot of Hoop-Woods scale amino acid sequence of a protein on its x-axis, and degree of hydrophobicity or hydrophilicity on its y-axis using python language as architecture by utilizing various functional attributes such as scipy, matplot and numpy modules. A case study has been reported using siallidase-4 enzyme. The program code can be available on request... View More»
DOI:
10.4172/jpb.1000182