Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Abed Namavari
Tanzania
Research Article
Efficacy of Intravitreal Injection of Tissue Plasminogen Activator on Improvement of Visual Acuity and Decreasing the Rate of Complications in Retinal Vein Occlusion
Author(s): Ahmad Mirshahi, Mahnaz Abdollahian, Alireza Lashay, Abed Namavari, Hooshang Faghihi and Mahdi NiliAhmad Mirshahi, Mahnaz Abdollahian, Alireza Lashay, Abed Namavari, Hooshang Faghihi and Mahdi Nili
Purpose: to evaluate the effect of Intravitreal tissue plasminogen activator (r-tPA) injection on improvement of visual acuity and decreasing the rate of complications in Branch Retinal Vein Occlusion (BRVO) and ischemic Complications in Retinal Vein Occlusion (CRVO). Methods: 10 patients with BRVO and 19 patients with ischemic CRVO of recent onset (from 4 to 30 days duration) and visual acuity of <=20/50 were given 100 microgram of tPA intravitreally. Ischemia was defined as an area of nonperfusion >=10 DD for CRVO and >=5 DD for BRVO. Follow up schedule contained 6 visits : at the time of injection, and 1 week,1 month, 2months, 3months, and 6 months after. Fluorescein angiography was performed before injection and at the end of the study. Results: In ischemic CRVO group: only one eye (5.6%) developed Iris neovas.. View More»
DOI:
10.4172/2155-9570.1000228